«Microbiota era» for public health
DOI:
https://doi.org/10.22141/2306-2436.9.4.2020.219249Keywords:
microbiota, integral model, gastrointestinal tract, prevention, public healthAbstract
Background. The coming decades are recognized to be the "microbiota era", a period of effective work of specialized scientific institutions around the world including Europe, with rapid growth of important aspects of various microbiota being discovered, using new non-cultural molecular genetic methods of diagnostics. The urgency of the research is to attract attention of medical community to scientific and practical potential of human microbiome. The application of integral model for systematization of diseases influenced by microbiota, as well as modulation of factors providing positive potential for human health, will optimize the quality of population health and the level of health of society. The purpose of the study was to assess the potential of human microbiome and substantiate the priority of integral model for studying the impact of microbiota on the human organism and the health of society as a whole. Materials and methods. Application of complex approach study methods, systemic analysis and own observations. Results. On the basis of integral perception of human microbiome, its colonization of organs and systems with a wide range of their mutual influence is clarified. The article focuses on the prospects and features of diagnostic methods, systematization of diseases influenced by microbiota, taking into account their comorbidity. Gut microbiota is characterized in details, it being a frequent predictor of definite diseases of organs and systems. Ways of screening optimization measures to prevent imbalance in biocenosis have been worked out which are supposed to help clinicians in promoting human health preservation. Conclusions. The suggested conceptual model of integral approach will extend understanding of microbiota impact degree on human health, prediction of disease and its course. Effective professional cooperation of scientists (availability of screening methods) and clinicians (wide use of integral system of preventive measures, modulation of microbiota) will improve the potential of human health and, accordingly, the level of public health as a whole.
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